The Bioconductor package coseq
The package coseq is devoted to the co-expression analysis of sequencing data. It contains the Poisson mixture models developed in HTSCluster (see below), the strategy based on Gaussian mixture models on transformed profiles (see Rau and Maugis-Rabusseau, 2018 for more details) and the use of the K-means algorithm for RNA-seq profiles after transformation via the centered log ratio (CLR) or log centered log ratio (logCLR) transformation (see Godichon-Baggioni et al, 2019).
Bioconductor coseq page [here](external_link: https://bioconductor.org/packages/release/bioc/html/coseq.html)
A quick-start guide is available here
Maintainer: Andrea Rau